The pathogenic mechanism in autoimmune response can be ascribed to the Coombs immunological classification of immune reactions.
1. Pick one autoimmune disease and describe the immunological mechanism(s) within the Coombs classification of immunological reactions that pertains to the pathogenic mechanisms within your disease.
2. In the treatment of the disease, what is the goal of the treatment, how successful is/are the treatment(s), what is the target of the treatment and the mechanism by which it modifies the individual disease.